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Kampmann Lab – Junior/Assistant Specialist
Kampmann Lab – Junior/Assistant Specialist The Kampmann lab develops and uses innovative technologies to understand cellular and molecular mechanisms of human diseases and to discover new therapeutic strategies. A major focus of our research is on neurodegenerative diseases such as Alzheimer’s and Parkinson’s Disease. To this end, we have established a CRISPR-based functional genomics platform for genetic screens in both human iPSC-based and murine models of disease (Tian et al., 2019, Neuron; Ramani et al., 2023, bioRxiv). We are an interdisciplinary group of postdocs, graduate students and staff research associates. We are proud of our lab culture of intellectual curiosity, collaboration, support, and fun! Read more about our lab at kampmannlab.ucsf.edu. In this position, you will be working as a member of a research team developing innovative, CRISPR/Cas9-based functional genomics approaches to understand the disease mechanism and to identify potential therapeutic strategies. You must be willing to work in a team, be organized, enjoy problem solving, and have strong communication skills. As you become familiar with our methodology, there will be opportunities to work independently on research projects. Based on your interest and expertise, you will be able to contribute to bioinformatics analysis of data as well. Responsibilities primarily include working under the guidance of a graduate student or postdoc to conduct experiments using murine models of disease, primary neuronal cultures, and mammalian cell culture. This involves performing in vivo experiments such as delivering viral vectors into mice, collecting brain tissue, sectioning and immunostaining tissues, confocal imaging, flow cytometry, preparing samples for next-generation sequencing and analysis of the resulting datasets. The candidate will also support collaborative projects that require the use of the lab’s CRISPR-based mouse in vivo screening platforms. Approximately 30% of the time will be spent on mouse colony maintenance tasks including setting up mouse breeding cages, weaning, tail/ear clipping, genotyping, promptly responding to mouse health concerns, updating the mouse inventory database, and other administrative tasks related to the mouse facility and IACUC protocols. A two-year commitment is preferred; and the candidate must be able to make a one-year commitment. Education and Training Qualifications: Technical Qualifications Preferred: Candidates must meet the required qualifications at the time of appointment. Candidate’s CV must state qualifications (or if pending) upon submission. Please apply online at https://aprecruit.ucsf.edu/JPF05956 with a CV, cover letter, and three references contacts. See Table 24B for the salary range for this position. A reasonable estimate for this position is $55,000 - $70,700.
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